Posted by Larry Hoover on November 7, 2004, at 11:23:53
In reply to Re: Sleep, etc. » Larry Hoover, posted by KaraS on November 4, 2004, at 15:12:13
> > Your hypothesis is that you have hypersensitive DA autoreceptors. You could look at the selegiline/DLPA experiment as a test of the null hypothesis.
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> But I have taken selegiline and it does put me to sleep. That confirms the hypothesis, no?I dunno. I don't think you did the DLPA part, right?
Sleep is a very complicated process. If you watch and listen to this flash presentation, you may get one of those intuitive aha's....
http://www.medscape.com/viewprogram/2791?src=search>My concern is could the continuous taking of selegiline do harm to the autoreceptors perhaps by making them more hypersensitive? I'd rather try to figure that out theoretically than empirically.
I don't know that you can. I'd wonder what led to hypersensitivity in the first place. Was it acute? Chronic? Did the situation remit/revert over time? (I.e. has the hypersensitivity gone away again?)
I can only shrug.
Lar
poster:Larry Hoover
thread:387192
URL: http://www.dr-bob.org/babble/alter/20041022/msgs/412878.html