Posted by KaraS on November 9, 2004, at 11:47:57
In reply to Re: newsweek article on mental health.., posted by sabre on November 9, 2004, at 2:39:22
> I agree, the article is very interesting.
>
> Kara you mentioned that you have a dopamine autoreceptor problem. Can you tell me more about that?
>
> Thanks
> sabre
I react paradoxically to stimulants/dopaminergics. They don't stimulate me as they do most people nor do they calm and focus me as they would to someone with ADD. Instead, they put me to sleep. I came across an article by Dr. Jay Goldstein that said for people who react like this to stimulants, it is thought to mean that they have "hypersensitive presynaptic dopamine autoreceptors". Dr. Goldstein claimed to have seen a lot of this in his CFS patients. I also have CFS. The net effect of this problem is that I have too many (they call it too "dense") of these autoreceptors. They are too vigilant in not allowing much dopamine to stay in the synapses of my brain. I don't know which dopamine receptors are involved or exactly which areas of the brain are involved either. I just know that my next moves should be in trying to downregulate them - which apparently is no easy feat.Do you think that this is your problem as well?
Kara
poster:KaraS
thread:413185
URL: http://www.dr-bob.org/babble/alter/20041108/msgs/413799.html