Posted by SLS on June 7, 2022, at 7:38:44
In reply to Re: Oral deprenyl vs bupropion?, posted by SLS on June 7, 2022, at 7:28:09
I forgot to mention that taking L-deprenyl / selegiline orally is not terribly effective. I tried sit many years ago. I don't remember the pharmacological reasons for this, but I believe oral administration produces far less circulating selegiline. I think it might be broken down in the gut.
Regarding selegiline and needing dosages high enough to inhibit MAO-A in order to obtain an antidepressant response:
https://pubmed.ncbi.nlm.nih.gov/10418793/
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1119824
URL: http://www.dr-bob.org/babble/20220530/msgs/1119851.html