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Re: Memantine as a reversible MAO Inhibitor?

Posted by g_g_g_unit on October 25, 2009, at 0:21:17

In reply to Memantine as a reversible MAO Inhibitor?, posted by Rosy Crucifiction on October 15, 2009, at 13:07:33

reading over your first post again .. "Memantine at 1mM inhibited both MAO-A and MAO-B activities in mouse forebrain homogenates to 37% and 64% of controls, respectively. "

5-HT and dopamine reuptakes were inhibited to 2% and 16% of controls, respectively, with 1mMmemantine. "

i mean, what do those figures mean anyway? is 37% and 64% MAO-A and B inhbition a significant amount, etc.? how would they compare to standard irreversible MAOI's?

 

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poster:g_g_g_unit thread:921016
URL: http://www.dr-bob.org/babble/20091021/msgs/922322.html