Posted by ed_uk on November 28, 2005, at 13:36:59
In reply to SSRIs..thumbs down.., posted by med_empowered on November 28, 2005, at 2:57:21
>Basically, the idea is that there was a swing towards "clean" drugs--drugs that just hit serotonin, for instance--and now there's a swing back to what would have been called "dirty" drugs but are now called "multi-target" drugs, or whatever. Same thing with the atypical antipsychotics--one of their selling points is that they tend to hit LOTS of stuff, not just the D2 like the old drugs...but they're not called "dirty" drugs, like TCAs are...no, they're called "multi-targeted" drugs, or whatever term is being used now.
So true. Haloperidol (Haldol) is a pretty 'clean' drug in terms of it's receptors affinities ie. it's a potent selective D2 antagonist. Unfortunately, 'clean' drugs are not always better.
Ed
poster:ed_uk
thread:582599
URL: http://www.dr-bob.org/babble/20051126/msgs/583015.html