Posted by flipsactown on April 11, 2005, at 15:02:58
In reply to Re: Flip???, posted by reefer on April 11, 2005, at 13:48:20
I am Asian which really throws a curve on your stats. I urinate frequently, and I think that may have something to do with it? I don't know, but I am still getting adequate pain relief for a couple of hours. Since I take it 5 times a day, every 4 or 5 hours, I am not completely pain free, but this is better then no relief.
FST
> This makes me think you have impaired enzyme function. The codeine isn't being converted to morphine in your body. Poor metabolizers with impaired enzyme function (Cytochrome P450 2D6) comprise approximately 7% of Caucasian, 2% of African American, and 1% of Asian populations.
>
> Actually i'm a poor metabolizer of CYP2D6 myself, and codeine does have an effect on me, BUT it doesn't kill pain(doesn't work as an analgetic). So while still binding to opioid receptors, codeine might not be very addictive when not converted to morphine in the body.
poster:flipsactown
thread:479222
URL: http://www.dr-bob.org/babble/20050408/msgs/482891.html