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Re: Omegabrite - Fish oil - EPA only - Thanks.

Posted by Hyena on August 21, 2011, at 8:40:29

In reply to Re: Omegabrite - Fish oil - EPA only - Thanks. » Hyena, posted by SLS on August 17, 2011, at 20:45:21

ok i got that a little bit wrong. this was the study i was thinking about.
http://archpsyc.ama-assn.org/cgi/content/abstract/59/10/913
"All of the individual items on all 3 rating scales improved with the 1-g/d dosage of ethyl-eicosapentaenoate vs placebo, with strong beneficial effects on items rating depression, anxiety, sleep, lassitude, libido, and suicidality."
here the 1 gram group did better than the 2 or 4 gram groups. i see with myself that if i take too much EPA i get less of an effect. there seems to be a sweet spot.
in my case i do better without any DHA. when i first started taking fish oil i was taking almost 1:1 epa:dha on an empty stomach and that was working well. over time though i was getting less of an effect so i started taking a 7:1 epa:dha supplement with food. this gave me a much more stable mood and ive been on it ever since. DHA competes with EPA for absorption.
EPA has though made me hypersensitive to some other supplements, e.g. b6. i can only take a very tiny about of b6 when im taking EPA or else i get terrible depression and anxiety. i think it just boosts the effect of other nutrients and sometimes this can be too much for the brain. i always was slightly sensitive to b vitamins anyway.

> Hi.
>
> > just wondering what dose of EPA you were taking.
>
> I was taking 800mg EPA and 500mg DHA.
>
> > do you know that some studies showed an improvement with 1 gram but a worsening of symptoms with 2 or 4 grams?
>
> Wow. I never encountered anything like that in the medical literature. What do you think is the optimal EPA/DHA ratio?
>
> > i take 1.5 grams of a highly concentrated EPA supplement spread out thoughout the day. if i take any more than this or if i take it all together at once i get no effect whatsoever. interestingly at the start i could take 3 grams and get a really good effect but had to lower the dose over time to keep it working. taking too much seems to trigger something that is counterproductive. maybe you just need to lower your dose.
>
> I'll keep that in mind.
>
> Thanks for sharing your knowledge and experience.
>
>
> - Scott


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poster:Hyena thread:992279
URL: http://www.dr-bob.org/babble/alter/20110810/msgs/994438.html