Posted by bleauberry on October 28, 2009, at 17:45:14
In reply to Re: hypomania or overstimulation? SAM-e / tyrosine » bleauberry, posted by g_g_g_unit on October 27, 2009, at 21:43:53
> thanks for your helpful post. it's strange because when i supplement with b6, folic acid and methyl-b12 (which supposedly converts into S-AMe?) i don't get the same reaction as supplementing with pure S-AMe; like i say, the former provokes a calm, but near-schizoid state in me, where as pure S-AMe is far more pleasantly stimulating.
Maybe a roadblock in the B metabolism somewhere? SAMe is like a short-cut bridging the roadblock?
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> if i repeat the experiment (depending on where my Parnate trial goes), i may try a lower dose, like 200mg of S-AMe every second day (i assume you can't cut the enteric tablets?).You can cut the enterics. They lose a tiny bit of potency, but not much. You can dismiss the internet claims that it must be taken whole. My own experiments and others have confirmed that SAMe can definitely be felt even when the enteric tabs are cut into quarters or halves. Theory is trounced by actual experience.
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> likewise, i only dabbled with N-acetyl-tyrosine. 300mg (the dosage it comes in) was way too much (i felt really tense and dysphoric), but 75mg was pleasant. i imagine since NALT is more potent than tyrosine, i could get away with a tiny dose.I wouldn't pay attention to the dose. Pay attention to the feel. If it is 10mg that fixes your chemical imbalance, then so be it. If someone else's chemical imbalance requires 1000mg, so be it. You have to find your own dose, which may be dramatically higher or lower than your best predictions.
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> i also have inhibiting substances on board - my (admittedly roughshod) plan for OCD w/ executive function difficulties was to try and combine something stimulating like S-AMe with a modestly therapeutic dose of inositol.
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I seriously doubt you will find inositol helpful for that purpose. The other agents I mentioned are much better, faster, and more direct.
poster:bleauberry
thread:922189
URL: http://www.dr-bob.org/babble/alter/20090727/msgs/923168.html