Posted by g_g_g_unit on October 25, 2009, at 5:33:27
In reply to Re: hypomania or overstimulation? SAM-e / tyrosine, posted by TenMan on October 24, 2009, at 10:49:58
> SAM-e is a wonderful compound which works almost instantly to relieve my depressive symptoms which mirror yours. Unfortunately I have found that it also can make me quite irritable. Interestingly in combination with Alpha-GPC, a choline donor, the irritability is relieved substantially. I would probably continue using the combination if the cost weren't prohibitive. But the two did provide most of what my body seemed to need and relieved substantially my anhedonic symptoms and executive dysfunction.
>
> I know someone who had great success on SJW and tyrosine combined so maybe you could try that?
>
>i guess the irritability was an NE thing which choline would antagonise? what dose did you try? apparently you're meant to stay on a certain dose to start with (200/400mg or whatever), and then *lower* it as it builds in your system - from what i've read in some places anyway.
there's some studies where methylation changes induced personality changes in rats. on methyl-b12, b6 and folic acid i fell into a kind of internalized, schizoid state, so i hope the same thing doesn't happen with too much S-AMe :/
poster:g_g_g_unit
thread:922189
URL: http://www.dr-bob.org/babble/alter/20090727/msgs/922341.html