Posted by Larry Hoover on May 26, 2005, at 22:47:37
In reply to Re: Magnesium orotate, uridine, arachidonic acid » Larry Hoover, posted by JLx on May 26, 2005, at 21:25:31
> > I don't think the intention is to get 500 mg/day of elemental magnesium from magnesium orotate supplements, is it? It's to take 500 mg of the complex, which just happens to be mostly orotic acid by mass (orotic acid is a pretty large molecule, and magnesium is a single atom).
>
> I was just thinking of 500 mg if one wanted to replace other forms of magnesium with magnesium orotate. You're saying the actual amount of magnesium doesn't matter?Mag orotate isn't a good source of magnesium, but it's a balanced source of the magnesium/orotate that seems to dock best into that enzyme active site. So, more magnesium wouldn't be adverse, and you could certainly get that from your usual citrate/malate/chelate or whatever.
> > Yes, it looks like orotic acid is better than lecithin. And citicholine perhaps better still. That does not mean, however, that the two cannot work together in harmony. If you supply two parallel metabolic pathways simultaneously, you tend to promote those aspects of each pathway (the alternate routes) which are not congruent. So, I'd wager that lecithin plus citicholine is better than just citicholine. Of course, I plan to try it alone, and in concert with fish oil.
> Lecithin is one thing I'm not sure I have a good result with. It seems like I always end up NOT taking it, if you know what I mean, in kind of a intuitive process. So I wondered if CDP-choline might be different.I just found a really cheap source of what is supposed to be the proper lecithin granules. Some are produced by a really inferior process, or something. I'm not sure what I've been getting locally, so I'll compare them.
Or do you use the lecithin oil caps? I don't use those, so maybe we're experiencing different substances/effects?
> > The oxidation products of arichidonic acid accidentally formed upon cell death are coincidentally the same ones that are purposely released to signal inflammatory processes. The end result is the same; the arichidonic acid cascade is indeed predominant in depression. Chicken or egg, who knows.
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> Yes, that's always the question, isn't it?
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> JLIn the end, if it makes you feel better, do it again. If it made you feel worse, don't. All the rationalizing in the world won't affect the empirical results.
I'm trying hard to not get too encouraged by the uridine/chronic fatigue link. Finding something that works for chronic fatigue would be a total blessing.
Lar
poster:Larry Hoover
thread:481903
URL: http://www.dr-bob.org/babble/alter/20050510/msgs/503426.html