Posted by sfy on October 18, 2004, at 23:07:06
In reply to Re: Selegiline Phenylalanine » sfy, posted by karaS on October 18, 2004, at 13:03:59
> S,
>
> How much longer are you going to give it? You must be so discouraged (as was I) after reading about the incredible success others are finding on this combination.
>
> How have you reacted to other dopaminergics? They tend to put me to sleep which has led me to explore why. Although I will say that on 5 mg. of selegiline (without the DLPA), it made me sleepy but many hours later provided a stimulant effect. When I once combined it with a little DLPA, I did get a bit shakey. I then made the mystake of eating a little chocolate and was very shakey. So I think I was getting the PEA effect but the dopamine itself was a problem. Does that make sense? I don't know if I were to take them both together consistently whether I'd get the downregulation I am hoping for... but my gut tells me that I won't.
>
> KKara,
I'm probably going to give it until my supply runs out (about 2 more weeks). I just wish it made me sleepy. My recurrent insomnia popped back up a couple of months ago (probably a sign of re-emerging depression). I had to go off the mirtazapine I take for insomnia when I started the selegiline. I went through exhausting early morning awakening which just dragged me down. I started some Benadryl which helps a little but it's not as effective as the mirtazapine.
I haven't taken any other pure dopaminergics before. I was on a brief trial of Wellbutrin but I'm not sure we gave it a fair shot (it also seemed to cause sexual problems but other factors might have been at play). I also took Nardil for over 2 years. It helped my social phobia but it's hard to say about other positive effects since I hadn't yet identified my anhedonia/dythymia then. I stopped taking it because of severe insomnia and thought I was well-equipped after CBT to handle things.
My next step is probably Parnate but I'm a little wary despite of (and because of) my experience with Nardil. The insomnia issue is a big deal for me. After Nardil, the insomnia lingered for a long time which is why I was taking the mirtazapine. The diet is also a concern even though I had no problems with it before. But I don't see very many other options right now. (Some have suggested Cymbalta but I don't see it have major impact on my issue based on reports on the main board.)
poster:sfy
thread:377600
URL: http://www.dr-bob.org/babble/alter/20040928/msgs/404571.html