Posted by SLS on January 15, 2023, at 11:24:04
In reply to inositol?, posted by PeterMartin on January 15, 2023, at 1:37:33
> Has anyone given inositol a try for anxiety (or depression)? I had some that I never gave a trial of and took some last night to try to quell some anxiety post ritalin. It did help and pretty quickly. I'm just not sure if there's a real risk of mania or depression being that I'm BP1.
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> If anyone has any experiences I'd be interested in hearing them.
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> Thanks!I apologize for writing stuff that doesn't directly apply to your question.
The only comment I can offer you is that Robert M. Post, MD of the National Institutes of Health (NIH) still includes inositol in the treatment of mood disorders, including treatment-resistant depression. He still has a private practice in Chevy-Chase, Maryland, but he charges $500 per hour for a phone consultation. Truthfully, I was not at all impressed with the results of a friend's phone consultation with him. My friend would best be described as being somewhere along the bipolar spectrum. I think inositol would make a good adjunct to lithium in bipolar depression, and perhaps unipolar depression as well. For most of his career, Dr. Post has been most interested in treating bipolar illness with mood stabilizers and substances usually described as being "nutriceuticals".
As I see it, the problem with Dr. Post is that he still adheres to an old school of thought that doesn't allow for giving antidepressants to treat any kind of bipolar disorder. Of course, I don't think that this should be applied universally. Were I being treated by Dr. Post, I would be depressed for the rest of my days.
Given all of that, I think inositol is one of the nutriceuticals most likely to help treat depression. It is used by the body to manufacture inositol phosphates and phosphatase enzymes. They are integral in the stabilization of neuronal and vesicular membranes. They also act as part of the post-synaptic second-messenger system and also modulate neurotransmission by facilitating the rushing of calcium ions from into the cell. These t also has its own receptor from which second messengers and calcium ion influx are activated.
N-acetylcysteine (NAC) is another substance worth exploring.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1121542
URL: http://www.dr-bob.org/babble/20220917/msgs/1121551.html