Posted by undopaminergic on December 16, 2022, at 10:19:41
In reply to Re: Finally trying vortioxetine -- initial impressions » undopaminergic, posted by SLS on December 10, 2022, at 8:11:59
> Hi again, UD .
Hi again SLS!
>
> I told my main research doctor at the NIH that I wanted to go to medical school. He was quite emphatic in recommending that I don't. He said that it would be too much stress on the brain. This is particularly true of not having a regular circadian rhythm as one does their internship in a hospital. The hours shift all the time. All of this combined would almost guarantee that I suffer a medication-breakthrough relapse. Remember, if you achieve remission, it will be under the conditions that you achieved it.
>I have no regular circadian rhythm when I'm left to my own devices and let my sleep-wake cycle be decided by how sleepy or how wakeful I'm feeling. When I'm using stimulants heavily, I'm up for days on end -- I pretty much make it a lifestyle. I think this may be regarded as a stereotypy.
>
> I am glad that your initial reaction was an almost instant improvement in depression. This is what the National Institutes of Health (NIH) called a "blip". They considered a TEMPORARY blip early during the course of a drug trial to be predictive of eventual treatment success - although not necessarily remission.
>
> Keep taking your antidepressants if this blip at the beginning comes and goes. You might have to wait 4-6 weeks to see the beginnings of a true clinical response.
>It's been blipping several times a day so far.
-undopaminergic
poster:undopaminergic
thread:1121240
URL: http://www.dr-bob.org/babble/20220917/msgs/1121262.html