Posted by undopaminergic on December 25, 2019, at 9:24:14
In reply to Re: atomoxetine works blissfully well at 40mg vs 140mg, posted by linkadge on December 25, 2019, at 8:15:42
> Atomoxetine will increase dopamine in the prefrontal cortex. The effect of dopamine in the prefrontal cortex is not linear (i.e. more is not always better). So, when you get to the level of optimal increase for you, taking more could actually worsen cognitive performance.
>
> Linkadge
>More specifically, working memory works (pun not intended) better when the dopamine is at the right level. alpha1- and alpha2-adrenoceptors are also involved. For the latter, there is guanfacine (Intuniv, Tenex).
-undopaminergic
poster:undopaminergic
thread:1107400
URL: http://www.dr-bob.org/babble/20191019/msgs/1107435.html