Posted by linkadge on April 17, 2018, at 7:19:55
In reply to Re: Buspirone causes insomnia? » linkadge, posted by SLS on April 16, 2018, at 22:29:42
I found that buspar and Effexor did mix well together.
If you think of it, buspar is supressing serotonin function (via presynaptic 5-ht1a agonism), yet increasing the release of catecholamines via presynaptic d2 antagonism and alpha-2 antagonism.
In other words (perhaps in the short term) it is shifting the sympathetic / parasympathetic balance.
When I first took low doses of buspar (5-10mg) I had almost total insomnia! This is strange, because it is a low dose of something that is supposed to be an anxiolytic.
Linkadge
poster:linkadge
thread:1098167
URL: http://www.dr-bob.org/babble/20180331/msgs/1098186.html