Posted by SLS on February 14, 2016, at 8:16:17
In reply to Perphenazine to replace Zyprexa, posted by Bob12 on February 13, 2016, at 6:13:26
I am unfamiliar with the use of perphenazine in treating OCD. I hope it works for you. The medical literature indicates that risperidone is good for OCD, but I believe it is used in conjunction with a serotonergic antidepressant.
Personally, I did not react well to perphenazine. It made me feel too drugged up. It was chosen to treat depersonalization and derealization when I was in my 20s. I have bipolar depression. I think perphenazine is less likely to produce EPS than the other older typical neuroleptic antipsychotics.
Have you tried CBT or exposure therapy in conjunction with pharmacotherapy?
Have you tried clomipramine (Anafranil)? The anticholinergic side effects are not much fun, but it may be the most potent OCD drug available. It would be interesting to investigate SNRIs like Effexor and Cymbalta. They usually have fewer side effects than clomipramine.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1086145
URL: http://www.dr-bob.org/babble/20160131/msgs/1086167.html