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Re: Parnate + Geodon safe?

Posted by tom2228 on May 5, 2014, at 23:02:45

In reply to Parnate + Geodon safe?, posted by Scatterbrained on May 5, 2014, at 21:06:39

> My doctor seems to think all atypicals are safe with maois but from what I read geodon more or less works as an SNRI combined with a neuroleptic. Definitely don't want to get into a toxic reaction . Does anybody have any insight into this?
>
> Currently on
> Parnate 40
> Zyprexa 5
> Lamictal 100

I would not recommend it

http://www.ncbi.nlm.nih.gov/pubmed/20631570
^(blank but another example)

http://www.highbeam.com/doc/1P3-2365106271.html
^"Tranylcypromine/ ziprasidone interaction"

"A 41-year-old woman developed serotonin syndrome during treatment with ziprasidone and tranylcypromine for severe depression.

The woman had been receiving ziprasidone 40 mg [frequency, route and duration of therapy not stated] and started treatment with tranylcypromine at 10 mg/day [route not stated] after a 14 day washout of other medications. On day 23 the dosage of tranylcypromine was increased to 50 mg/day in divided doses. The next day she experienced tremors, shivering, diaphoresis, fever, vomiting, diarrhoea and confusion. She was admitted to an emergency department in an agitated state with a fever of 38.5°, a pulse of 130 beats/min, hyperreflexia, shivering and myoclonic jerks of all four extremities requiring restraints. "


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poster:tom2228 thread:1065281
URL: http://www.dr-bob.org/babble/20140419/msgs/1065286.html