Posted by SLS on March 10, 2014, at 23:54:55
In reply to Re: Phidippus. - I see. My apologies. » SLS, posted by phidippus on March 10, 2014, at 14:53:11
> >Chalk that one up to the vestiges of my defensive self.
>
> Tell me about your childhood.
>
> And tell me about your medicine regimen.
>
> EricMy childhood sucked. It was full of parental physical and emotional abuse - that is, when I wasn't being totally neglected. At school, I was teased and bullied. There may be an element of PTSD (developmental PTSD) involved. I have been depressed since age 10. The most severe depression began at age 17, and has been chronic ever since - with the exception of a 2 year period during which I was an ultra-rapid cycler (11 day cycle). Bipolar disorder was diagnosed at the NIH. Severe, psychotic mania have occurred in association with antidepressant administration. The symptomatology of my depression is most similar to bipolar depression. Anergia, psychomotor retardation, hyperphagia, hypersomnia, early morning and late night improvement, unreactive, little or no rejection sensitivity, some melancholia and depressed mood, social anxiety, lack of interest, amotivation, poor concentration and memory.
Currently:
Parnate 100 mg/day
nortriptyline 150 mg/day
Lamictal 200 mg/day
lithium 450 mg/day
prazosin 25 mg/day
minocycline 200 mg/day
Abilify 10 mg/dayThis regime is tweaked in that each drug has demonstrated its value by attempting its discontinuation. Dosages have been optimized by careful titration. Dosages have been pushed and reduced as necessary.
I have tried most antidepressants. The notable exceptions are Fetzima, Brintellix, nefazodone, and doxepin. All AAPs except for Clozaril. Most all mood stabilizers. Augmentation with bromocriptine, amphetamine, methylphenidate, thyroid, memantine, Deplin, and other stuff.
MAOI + TCA has produced the best results, including one 6-month period of remission in 1987 using Parnate + desipramine. The doctor had me discontinue treatment as he said, "mission accomplished". Upon relapse, he refused to restart both drugs for fear of mania. I was never to respond robustly to treatment again.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1062167
URL: http://www.dr-bob.org/babble/20140307/msgs/1062236.html