Posted by ed_uk2010 on January 5, 2014, at 14:11:37
In reply to Re: old unused antipsychotics, posted by linkadge on December 30, 2013, at 20:16:17
> Some of the "typicals" are actually atypical. Perphenazine, for instance, actually has high affinity for serotonin 5-ht2a receptors (a quality deemed "atypical").
Most phenothiazines block 5-HT2a receptors, but are generally more potent at D2 receptors. Atypicals tend to be the other way around. In contrast to phenothiazines, haloperidol is not active at serotonin receptors.
poster:ed_uk2010
thread:1057164
URL: http://www.dr-bob.org/babble/20140104/msgs/1057876.html