Posted by SLS on February 1, 2013, at 12:21:16
In reply to Re: Prazosin - SLS need advice and info *please*!!! » SLS, posted by ChicagoKat on February 1, 2013, at 10:14:02
> Thanks for all the info Scott. I did find a couple mentions of prazosin beng used for anxiety, one in the wiki article.
>
> But one more question for you, if you have a moment....do you know the rationale for using prazosin for depression? Since it acts by blocking Norepi, I would think the opposite would be the result. But there is no doubt you are the expert, and I'd be very interested to hear what you have to say. Thanks so much.
> KatDon't think so much! It makes my brain hurt!
I am no expert.
Regarding prazosin, I would think that things are not so simple. I have a few ideas, though. It might be that a reduction of NE activity in the amygdala reduces anxiety and PTSD while a reduction of NE activity in the subgenual anterior cingulate cortex might be responsible for its antidepressant effect.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1036953
URL: http://www.dr-bob.org/babble/20130124/msgs/1037056.html