Posted by ed_uk2010 on February 24, 2012, at 16:47:37
In reply to Re: Daughter's Saphris Complaint, posted by Solstice on February 23, 2012, at 9:36:07
>But.. what's with the 'don't eat or drink for 10 minutes?'
Asenapine is very poorly absorbed when it is swallowed. It is mainly absorbed from the lining of the mouth. If she eats or drinks within 10 minutes, the drug is likely to be washed away from the lining of the mouth and swallowed.
>And my daughter says it makes her salivate - so what does she do with that?
> - Does she hold the saliva while it disolves, and then swallow it? or..
> - Is she supposed to spit the saliva out?If she spits the saliva out she would probably spit some of the dose out.
>What is the purpose of putting it under the tongue?To reduce the chance that the tablet will be swallowed. Also, the underside of the tongue is very vascular and this is good for absorption.
poster:ed_uk2010
thread:1011236
URL: http://www.dr-bob.org/babble/20120221/msgs/1011416.html