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Re: Leg jerks on serotonergic meds. . . » g_g_g_unit

Posted by ed_uk2010 on September 18, 2010, at 16:30:08

In reply to Re: Leg jerks on serotonergic meds. . . » ed_uk2010, posted by g_g_g_unit on September 18, 2010, at 1:48:40

>I'm only on 100mg, and have been experiencing them with each subsequent titration since I started at 25mg a week ago. Do you know what causes them, Ed? Is it typically a transient problem?

100mg isn't that low, clomipramine is powerful stuff. It can certainly be effective at 100mg, so I would avoid any further increases, at least for the next month or so.

Twitching of the legs seems to result from excessive increases in serotonin. It is particularly likely with combinations of more than one serotonergic drug. I think it is a sign that 100mg is more than enough.


 

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