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Re: venlafaxine 600mg + methylphenidate? » ed_uk2010

Posted by europerep on July 18, 2010, at 10:57:46

In reply to Re: venlafaxine 600mg + methylphenidate?, posted by ed_uk2010 on July 17, 2010, at 15:09:00

hm, well, I'm not sure if I'm so comfortable with being two weeks entirely without meds, that would surely be very very difficult... because even if I lower the current dose of venlafaxine only by 75 or 150mg, I notice a strong worsening of symptoms, I am no longer able to get up before noon or even later, etc.. but I will of course not refrain from trying MAOIs at the point where it is necessary, I just hoped to be able to go without them.

I now also "re-discovered" why I was hesitant about clomipramine the last time I considered it. apparently, it has been shown to be mutagenic in drosophila flies. of course that's just these tiny flies, but it scared me, especially in terms of "reproduction", since I am still relatively young. I am at a different point now though, and maybe I will just have to hope it works differently in humans. of course, clomipramine has been in use for a long time, but I could imagine that it is very difficult to trace back possible genetic changes, if they are ever discovered, to a certain medication, since there are so many factors in the environment that might have similar effects. hm, it's all difficult.

 

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