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PPIs » sukarno

Posted by ed_uk2010 on March 20, 2010, at 10:48:08

In reply to Re: Xanax on private prescription in UK » ed_uk2010, posted by sukarno on March 18, 2010, at 20:35:43

>When I was on lansoprazole (and separately omeprazole) I experienced a syndrome consisting of mental depression and malaise in the beginning and then progressing several days later into a full-blown dengue-like or severe flu-like illness (arthralgia, myalgia, pyrexia and tachycardia >120bpm which lasted 12 hours).

It sounds rather like a serum sickness-like reaction (Hypersensitivity Type III).

> There is a new PPI in Japan named tenatoprazole, which is not a substituted benzimidazole. Perhaps it won't produce the same reaction. Are you familiar with that PPI?

Not really, no. It's not a drug that we use here. I think it might be better to stick to the H2 antagonists. Ranitidine 300mg twice a day can sometimes be used instead of PPIs but even at this (high) dose it is less reliable.

 

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