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Re: SSRI's + extra pyramidal s/e's » linkadge

Posted by g_g_g_unit on February 1, 2010, at 7:43:57

In reply to Re: SSRI's + extra pyramidal s/e's, posted by linkadge on February 1, 2010, at 6:52:34

>
> This side effect may be more pronounced in people with 'low dopamine' to begin with. You may try a lesser dose of the SSRI.

i can't remember if it only occurred on higher doses or not .. but i'll keep that in mind this time. i think it was worst on Luvox, and i did take a higher dose of that. i didn't notice it as much on Lexapro.

> You might augment with something like >mirtazapine (or cyproheptadine / low dose TCA) >(which blocks inhibitory serotonin receptors). >Bupropion augmentation might offset this effect. >You might also get relief with a benzodiazapine.

remeron might be a good option because i also have difficulty with insomnia

>
> Another option is to switch to a TCA, mirtazapine or bupropion.
>
> A stimulant may help, but it may end up depleting dopamine more in the long run. An agent like coenzyme q10 might be beneficial as it has the ability to ameleorate drug induced catecholamine disturbances.

i know next to nothing about pharmacology but i was thinking of revisiting Memantine as an augmentation agent for OCD. since it's a D2 agonist and 5HT3 antagonist, is there any reason to think it might help the restless legs etc?

>
> Other options include tyrosine, caffiene or a dopamine agonist.
>
> Linkadge
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poster:g_g_g_unit thread:935554
URL: http://www.dr-bob.org/babble/20100122/msgs/935571.html