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Re: Why antidepressants don't work for so many » SLS

Posted by linkadge on October 25, 2009, at 17:30:55

In reply to Re: Why antidepressants don't work for so many, posted by SLS on October 25, 2009, at 15:53:26

It is you of all people SLS that I would expect to produce such a narrowminded responce.

You have always held that there are true neurobiological underppinings to severe chronic depression that many people experience.

You know something about the biological and structural abnormalities that are evident in depression. You, on many occasions, have expressed uncertainty as to whether these are a cause of or response to depression/anxiety.

To call this study absolute crap is to basically say the contrapositive. That is, that all depression is caused by stress. In other words SLS, there is nothing fundamentally wrong with you. The only reason you are depressed is because you are unable to deal with stress effectively.

Yes, that is what you are concluding by saying this study is crap.

Look folks, this isn't rocket science. All this study really concluded is that a group of mice (that have a gene profile that results in tendencies towards depression) is still fundamentally different than a group of mice which have simply been exposed to stress. It actually helps to verify the notion that there is something fundamentally different about depressed people.

Sure, if you want to go on believing that the reason you're depressed is becuase you have a stressful life then be my guest. It really doesn't help plead your case to the lay person (who already things depressed people are just a bunch of people too weak to handle the pressures of everyday life).

Note**, this study does also *not* suggest that stress can't be the straw that breaks the camels back so to speak. Its not unreasonable to suggest that the mice with both the "disease model" gene profile and "stress induced" induced gene profile didn't feel worse than either alone.

All it is suggesting is that the mice who had the depression like behavior before the stress had something different about them.

Think back to your life. So, if it was stress that made you depressed, how was your life before that? Would you have considered yourself perfectly well up until the point that stress caused clinical depression??

Research in humans does seem to suggest that even in people who do have depression that was triggered by stress, there were subtle behavioral differences before the onset of the first episode.

Did people even read the study. Do people even realize what it found??? - or do they just read the headline and disagree with that???

Linakdge


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poster:linkadge thread:922361
URL: http://www.dr-bob.org/babble/20091021/msgs/922435.html