Posted by linkadge on October 22, 2009, at 16:49:25
In reply to Re: scopolamine has messed me up?!! » linkadge, posted by rovers95 on October 22, 2009, at 5:04:46
You know, I'm not really concerned with cholinergic upregulation because most antidepressants produce a cholinergic upregulation. This is why anticholinergics like benadry can help with AD withdrawl because they reduce cholinergic rebound.
On the other hand, I would not (personally) use scopolamine long term for a depressive disorder. There is evedence of cholinergic dysregulation in depression but this is thought to be a downstream adaptation to...i dunno....second messenger dysregulation, g-protein something r uther.
There is also evedence that long term anticholinergic administration may actually worsen dyskinesia.I use scopolamine periodically when I am in a hypercholinergic state secondary to stress, sensory overload, overwork etc. It seems to quickly put me into a good zone where I can then
use other supplements to reregulate things.I sometimes use scopolamine in combination with magnesium/vitamin c. This combination seems to help me reset fast, and I don't get much withdrawl.
Linkadge
poster:linkadge
thread:921816
URL: http://www.dr-bob.org/babble/20091021/msgs/922005.html