Re: how does lyrica affect TCA levels???

Posted by bulldog2 on August 29, 2009, at 13:23:59

In reply to Re: how does lyrica affect TCA levels???, posted by SLS on August 28, 2009, at 11:26:04

> > i was just wondering if lyrica could enhance TCA levels or TCA AD effects or if it decreases the blood levels or the AD effects ??
>
> I don't know.
>
> Lyrica (pregabalin) is eliminated through the kidneys unchanged, much like Neurontin (gabapentin). Therefore, it would not affect the enzymatic metabolism of TCA. TCA levels should be remain unaffected.
>
> Whether or not Lyrica can enhance the antidepressant effect of TCA is hard to predict. Like so many combination treatments, it is really a trial-and-error process to evaluate a treatment's effectiveness.
>
> Are you bipolar?
>
>
> - Scott
Scott are you sure about lyrica and the kidneys? I know that's how neurontin works. But I thought the way lyrica was enhanced was it was broken down by the kidneys so you can have higher levels of the drug in your system.

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how does lyrica affect TCA levels??? fellowmike 8/27/09
Re: how does lyrica affect TCA levels??? SLS 8/28/09
Re: how does lyrica affect TCA levels??? » SLS fellowmike 8/28/09
Re: how does lyrica affect TCA levels??? » fellowmike SLS 8/28/09
Re: how does lyrica affect TCA levels??? bulldog2 8/29/09

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