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Re: Contramid(tm) » Chairman_MAO

Posted by SLS on June 1, 2009, at 6:16:01

In reply to Contramid(tm), posted by Chairman_MAO on June 1, 2009, at 5:55:05

Hi Chairman_MAO

I hope you have been well.

Thanks for posting this information.

- Scott


> I'd be interested to see if any compounding
> pharmacy could make e.g. 100mg tranylcypromine
> tablets with this stuff. I'd switch to that
> in a heartbeat if that were possible (200mg/day).
> In general, it seems like this stuff has
> potential, and so I just thought I'd mention it:
>
>
>
> Our lead technology platform, Contramid®, can be applied to a wide variety of drugs in solid, oral dosage form to optimize compliance, safety, bioavailability and performance.
>
> What Is It?
>
> Contramid is a cross-linked, high amylose starch drug delivery technology that meters the release of drugs from orally administered solid dosage forms.
>
> How Does it Work?
>
> In its dry state, Contramid acts as a free flowing, highly compressible powder. When in tablet form and wetted, it forms a long-lasting, uniform surface membrane that is ideally suited to controlled release of orally administered drugs under a broad range of in-body conditions.
>
> What Are Its Advantages?
>
> Contramid has the following advantages as a controlled-release technology:
>
> * High drug loading capacity (important for once-daily formulations);
> * Flexible release profiles to maximize efficacy and minimize side effects;
> * Ability to release multiple drugs from a single tablet with different release rates;
> * Safe: Contramid complies with FDA and EP regulations for modified starches and may be used in any proportion in oral pharmaceuticals. Being starch-based it is also completely biodegradable.
>
> What Have We Done With It?
>
> Our once-daily formulation of tramadol, now on the market in Europe, validates our Contramid technology in solid, oral dosage applications. We are currently working to exploit Contramids potential through a number of different presentations.

 

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