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is agomelatine a simple antagonist or inv. agonist

Posted by iforgotmypassword on March 5, 2009, at 9:35:06

...at 5-ht2c receptors? it appears many antipsychotics that are conventionally simply termed antagonists (at 5-ht2a or c receptors) are inverse agonists. does anyone know what agomelatine's effects relating to this are in full detail? and if its effects as a 5-ht2c antagonist have been accurately assesed with its short half life and once daily dosing.


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