Posted by bleauberry on February 2, 2009, at 16:34:46
In reply to Parnate., posted by Love24 on February 2, 2009, at 9:41:17
I don't know about the hunger thing, but I thought you should know you aren't the only one who has "sampled" parnate. :-)
At my last appointment my doc said she was open to giving me an MAOI but since they are rarely used around here she wanted to brush up her knowledge on them. The next appointment is next week.
In the meantime, I had already ordered Parnate mailorder from UK but hesitant to try it. I figured I had some time and since I am very very sensitive to meds, maybe I could just sample a small dose of Parnate so that if it goes badly at least at the next appointment I can go for Nardil or Marplan instead.
So I took a 10mg pill, cut it in half, and did 5mg around lunch time. Within 2 hours I felt noticeably worse, similar to how adderall did to me. About 6 hours after the dose I rebounded and felt noticably better than I had before the dose.
That night sleep was lousy. Very light sleep, hard to go to sleep, early waking. When I woke, I definitely felt worse. I've felt real bad at work so many times and have learned to put on a decent survival fake job to avoid others seeing it, but this day I got comments from people saying I looked so sad and and what was wrong. I had already decided Parnate was garbage for me.
The next day was a pretty good day. I would say maybe about a 20% improvement overall. I was impressed. The next day, another decent day. More impressed. Mind you, this was from a single 5mg dose 3 days earlier. Then I had 2 glum days and it felt like it was definitely wearing off. Then surprise, 2 more good days. Pains were much less, mood a bit better, not so glum, a bit more energy, a bit more interest and motivation. Sleep was good except for that first night.
After that mood went downhill rapidly and I developed some nervousness and anxiety that I haven't felt in months. I concluded MAO enzymes were coming back to life and not good for me.
The whole time my appetite was down. Unlike you. I just didn't feel much like eating.
So here a week later, and one week to go for the appointment, I am seriously considering doing another 5mg.
I think Parnate is some very potent stuff.
I had a genetic lab test done which identified I had double mutations on the MAO genes. I wasn't sure what that meant, but a clinician from the lab suggested taking very small very frequent doses of st johns wort and 5htp, which indicated to me that meant the MAO enzymes were too active. Nobody prescribes MAOIs around here, so no surprise they didn't. But, looking at the genetic profile, it is an obvious no-brainer.
I'm not going anywhere with this story. Just rambling. Thought I would share and compare experiences of our brief sample tests of parnate.
poster:bleauberry
thread:877625
URL: http://www.dr-bob.org/babble/20090104/msgs/877680.html