Posted by linkadge on January 29, 2009, at 19:39:13
In reply to AMOXAPINE is technically a SNDRI (i think?), posted by myco on January 29, 2009, at 14:25:03
I though the dopamine activity refered to dopamine receptor antagonism i.e. neuroleptic style.
Even at clinical doses, wellbutrin has very low activity as a dopamine transport inhibitor. I remmber reading as study that suggested at a dose of 300mg, it only inhibited the dopamine transporter by ~15%.
Wellbutrin has an effect on norepinephrine reuptake and also norepinephrine release. Some modern research has theorized that it is working via norepinephrine release.
Linkadge
poster:linkadge
thread:876477
URL: http://www.dr-bob.org/babble/20090104/msgs/877091.html