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Re: Making sense of NARDIL 'poop out' (benzo like?) » desolationrower

Posted by Vincent_QC on January 26, 2009, at 7:02:02

In reply to Re: Making sense of NARDIL 'poop out' (benzo like?) » Vincent_QC, posted by desolationrower on January 25, 2009, at 22:10:02

> well i'd guess that the poop-out-able effects of parnate are more due to AMP like catecholamine release. similar to the way AMP dosage needs constant and fast acceleratio to keep it euphoric.
>
> -d/r

Lol.... My god...are you sure you don't studies in the pharmacist field? ;-) That's a joke here...don'T take it personnaly... ;-)

By AMP you mean the amphetamine structure similar than the Parnate one??? It make a lot a sense...It's probably why I was sensible to the Parnate effect (augmentation of levels of dopamine, epinephrine, and norepinephrine into the blood stream), they affect my heart and my blood pressure.

Since the destruction of the MAO high the levels of catecholamines...I still wonder why I found the Parnate to be less stable and more high in side-effects than the Nardil?

The Nardil have a more neutral effect and is a more easy AD's with less to no side-effect at all, exception of the daytime sedation (Parnate also give more daytime sedation with time) and the orthostatic hypotension at high dosage...IS it because it's less efficiently than the Parnate???

I always think the Parnate was responsable of a more powerfull action on the monoamine oxidase B and the Nardil was more hard on the type-A...And I also link the MAO B to DA and NE and MAO A to SE...but now i'm confuse...since I read than the lack of MAO A high the levels of dopamine, epinephrine, and norepinephrine...I still don'T know now the actions of the MAO A and on witch neuortransmitters it work...the same apply for the MAO B...

But who know...I never found a study who show the amount of mao A or B who is destroy by the Nardil or the Parnate...I only know some informations about the Manerix who apparently, a simple dose of 300mg destroy 80% of the mao A and 30% of mao B...but anyway, i'm out of subject here and I hate the effects of the Manerix...too much anxiety increase on it and migraines...


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poster:Vincent_QC thread:875681
URL: http://www.dr-bob.org/babble/20090104/msgs/876265.html