Posted by CaptainAmerica1967 on January 15, 2009, at 20:29:58
In reply to Re: MAOI TX in Severe+Resistant Depression, posted by Cseagraves on January 15, 2009, at 14:21:06
Also, there are some other meds your physician my not be aware of that when used off label for anxiety, social phobia, agoraphobia, panic disorder, GAD, PTSD, can be very effective.
GHB (XyRem) or gamma-hyroxy-butyrate is a medicine indicated for narcolepsy and excessive daytime sleepiness. However, in smaller doses taken prior to going out to socialize or any thing or place that causes anxiety, it can do wonders. I've personally used it especially a very small amount prior to giving a speak to a large group and it makes you want to talk and more open and "inhibits" your fear kind of like alcohol does, but better. However, it can cause rebound anxiety and whenever I took it, I'd always take a very low dose of xanax to prevent the potential rebound anxiety. Testing is being done by Jazz Pharmaceuticals for multiple uses such as a socializing drug as well as other indications.
Oxytocin is the hormone of cuddle and helps us to fall in love as well as promote uterine contractions during child birth, but has some potential as an antidepressant, anxiolytic, and a socializing hormone. It's one of two hormones secreted by the posterior pituitary and is available by injection (used mainly by OBGYN's to induce labor) and as a spray (easier to take and crosses the blood brain barrier better).
D-Cycloserine is an antibiotic with interesting potential uses and some studies show individual taking it prior to a phobic event learn not to fear it.
Beta-blocking drugs like Inderal (propranolol) prevent the run away adrenaline fear one feels in a scary situation and some people take it prior to speaking (stage fright) or flying (acrophobia). However, Inderal can cause depression, but there's a more specific beta-blocker used to help depression called Viskin or pindolol which might help you.
poster:CaptainAmerica1967
thread:873284
URL: http://www.dr-bob.org/babble/20090104/msgs/874227.html