Posted by azalea on October 7, 2008, at 19:01:56
In reply to Need Help Obtaining Suboxone, posted by Shelly Dylan on October 7, 2008, at 17:21:26
Perhaps you could provide your doctor with following research study . . .
J Clin Psychopharmacol. 1995 Feb;15(1):49-57.
Buprenorphine treatment of refractory depression.
Bodkin JA, Zornberg GL, Lukas SE, Cole JO.
McLean Hospital, Consolidated Department of Psychiatry, Harvard Medical School, Belmont, MA 02178, USA.Opiates were used to treat major depression until the mid-1950s. The advent of opioids with mixed agonist-antagonist or partial agonist activity, with reduced dependence and abuse liabilities, has made possible the reevaluation of opioids for this indication. This is of potential importance for the population of depressed patients who are unresponsive to or intolerant of conventional antidepressant agents. Ten subjects with treatment-refractory, unipolar, nonpsychotic, major depression were treated with the opioid partial agonist buprenorphine in an open-label study. Three subjects were unable to tolerate more than two doses because of side effects including malaise, nausea, and dysphoria. The remaining seven completed 4 to 6 weeks of treatment and as a group showed clinically striking improvement in both subjective and objective measures of depression. Much of this improvement was observed by the end of 1 week of treatment and persisted throughout the trial. Four subjects achieved complete remission of symptoms by the end of the trial (Hamilton Rating Scale for Depression scores < or = 6), two were moderately improved, and one deteriorated. These findings suggest a possible role for buprenorphine in treating refractory depression.
> I've suffered from severe refractory depression for over 21 years. The only thing that works are opiates. They make me feel normal not high. I can't find a doctor who will prescribe them to me thanks to our "wonderful" DEA. What do I do? I need help. I don't want to live the rest of my life depressed. I don't understand how physician's, in part thanks to the government, can refuse to give me medicine that will help my condition. Someone, anyone, please help.
poster:azalea
thread:856260
URL: http://www.dr-bob.org/babble/20081006/msgs/856287.html