Posted by superman on August 21, 2008, at 12:56:30
In reply to Re: Wellbutrin/stimulant poop-out--pls help w/ ide » MattSanz, posted by raisinb on August 16, 2008, at 10:23:44
Hi,
I agree 100% with what raisinb said... the brain/mind is an amazingly complex system, and there is much more to the story than level of this or that neurotransmitter.Indeed, depression or worse anxiety, or even increased chanced of suicide are pos sible side effects for most psycho-active meds, even if they are *meant* to fight depression or anxiety or whatever. Everyone reacts differently. The truth is we don't really have a good understanding of how most of these meds really do work (when they do) or what's going on in the brain. The best we ever have is somewhat educated guesses.
I believe just because you get a good response initially does not mean it's a good bet for help long-term. In fact, if looking for long-term relief, this may not be desirable. bleauberry mentioned feedback-loops, and that is important to keep in ind. This is why we don't all just do crack cocaine to fight depression, because feedback-loops are at work, and tolerance will set in - so obviously crack is a horrible choice for long term relief, despite that you'll likely feel great the first while while on it.
Anyhow, sorry to ramble. My advice, if it means anything, would be to try something else. Wellbutrin doesn't seem to suit you - I wouldn't be thrown off by the fact you felt good on it for the first short while. Further, I don't see any good reason why this "sub-therapeutic dose" idea would be any better if it made things worse at the higher dose.
Good luck and all the best.
-T> From what I've read, any antidepressant *can* cause increase in depression/suicidal ideation. Many people say that this is why the "chemical imbalance causes depression; raise the chemicals and fix the depression" theory is crap (or at least way too simplistic.) Depression may have a different cause altogether--or, more likely, multiple different causes for each person.
>
> It might be that more dopamine just didn't help oceancat. Maybe stimulation of something else is what's needed. At the very least, IMHO, all these neurotransmitters work in a delicate balance and too much of a good thing is as bad as not enough. After all, vitamins and minerals work that way.
poster:superman
thread:846321
URL: http://www.dr-bob.org/babble/20080814/msgs/847530.html