Posted by SLS on May 28, 2008, at 7:18:37
In reply to Doxycycline and mood swings, posted by cactus on May 27, 2008, at 21:32:05
> Has anyone experienced this? I just got back from holidays and it was a malarial zone. I didn't know if it's just me or a common side effect of doxy? Also on modafinil and clonazepam.
Doxycycline has anti-inflammatory properties that some speculate are helpful to treat depression, as depression is often associated with an elevation of cytokines.
Q: During your mood swings, did you feel that the depressive phase was worse than your untreated baseline depression?
It is possible that the doxycline is in the process of resetting your mood in order to stabilize it at a higher, less depressed level. The path that this process might follow may include frequent adjustments taking place in the brain. Sometimes, one first feels worse on doxycycline before feeling better.
I'm really reaching on this one.
I tried doxycycline to treat my depression. One must give it 3-6 months to work. My doctor suggested this. It did not help at all, but neither did it hurt.
I am hoping that if you stick with it, you may derive some benefit. If you've been on doxycycline for more that 3 months and remain feeling worse on it, you might as well discontinue it if you no longer need it for malaria prophylaxis.
- Scott
poster:SLS
thread:831517
URL: http://www.dr-bob.org/babble/20080528/msgs/831586.html