Posted by undopaminergic on April 18, 2008, at 7:18:12
In reply to Too Much Nardil??, posted by maoi_wowee on April 16, 2008, at 21:27:07
> I was on 75mg of Nardil, did great for a few weeks, then depression started to come back so I upped dose to 90mg. Did OK for a few weeks at 90mg, but now my depression has started to come back again.
>
> Any chance that things could get better by decreasing my Nardil dose? Or perhaps by decreasing it down a bunch then upping it again and keeping this cycle going?
>
> Any thoughts/help? I'm lost and desperate
>They say it's more about time than about dose.
However, dose is certainly not without significance, as it affects the level of MAO inhibiton.
Some sources recommend 1 mg phenelzine per Kg body weight. However, up to at least 135 mg may be necessary. Even then, it may be necessary to add a stimulant - see:
http://www.dr-bob.org/tips/split/MAOIs-in-high-doses-and-wi.htmlPersonally, I would rather start with a stimulant at high doses, and then add the MAOI, preferably rasagiline, as this would minimise the risk of complications arising from MAO inhibition (dietary and drug interactions).
poster:undopaminergic
thread:823684
URL: http://www.dr-bob.org/babble/20080412/msgs/823980.html