Posted by undopaminergic on April 13, 2008, at 0:05:21
In reply to Re: Info on stablon and valdoxan » undopaminergic, posted by Racer on April 11, 2008, at 10:14:52
> > Is there a reason (assuming equal price and availability), for using bupropion (Wellbutrin) or piribedil (Trivastal) rather than methylphenidate or modafinil (
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> For some people, the reason would be the abuse potential of methylphenidate or modafinil. That may fall under the "equal availability" clause in your question, but it's still well worth remembering. I've taken methylphenidate for some time now, and sometimes worry about the abuse potential myself. (That's part of my OCD-spectrum symptomology.)
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> Also, there's more than just the stimulation to consider. Wellbutrin is an antidepressant with a more activating profile, and may therefore be more appropriate for many people than a conventional psychostimulant. Trivestal is a dopamine agonist, which may have an effect on anhedonia, or may not, but isn't likely to have a direct effect on depression.
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> I guess what I'm trying to say is that there are some pretty good reasons to use Wellbutrin, or Trivestal, just as there are some good reasons to use methylphenidate or modafinil -- they're just different reasons...
>I suppose I was wondering more about the particular reasons in the case of the poster, other than the possibilities I had already considered (availability and price). I'm interested in comparative experiences and findings regarding these drugs all having a dopaminergic mode of action.
My experience is that a dopmine agonist - pramipexole (PPX) - was more "euphoric" or mood-elevating than methylphenidate (MPH), but it had more side-effects and lost all effectiveness in a few weeks, whereas MPH retains at least some of its usefulness (at increased doses) for over a month at a time. I haven't tried Wellbutrin because I've presumed it would be less effective and have more side-effects than MPH, but also because in my case price and availability favoured PPX and MPH.
What sort of abuse potential do you worry about? Snorting all your tablets in a binge for a euphoric high, or using them to stay awake for way too long? I'll admit that I've used or abused stimulants for the latter purpose, but I don't worry about it (it's no big deal since the prolonged sleep that automaticaly follows will make up for any sleep deficit).
poster:undopaminergic
thread:822072
URL: http://www.dr-bob.org/babble/20080412/msgs/822999.html