Posted by iforgotmypassword on December 14, 2007, at 5:25:47
In reply to Re: Ketamine Trial, posted by linkadge on December 13, 2007, at 22:20:44
yes, i do believe the doses they are using are much lower than anaesthetic or even recreational use, but i am just guessing.
another NMDA antagonist, but weaker: memantine, i am thinking of trying again soon, along with the lamotrigine (150mg currently). i hope this combination isn't contraindicated, it's a pretty anti-glutamate combination, i'd gather. i've responded to it before. memantine seems to "sober" you, or that's how it feels, but i imagine maybe to other people you may seem a little "gone" and drunk on something else. you don't laugh as easily, but i don't remember if it really makes you find things less funny. i think it may just help you not fall into inner emotional impulses that can be hard for your nerves to resist. i do kind of worry that it slows you, which i guess i'll find out if it did. i'm hoping it helps my focus and makes me more observant and objective, and less overwhelmed by weighty emotional attitudes and prone to keep paralysed. i found adding lamotrigine to memantine out of the blue to be very unparalysing.
i'm hoping this effect lasts and isn't a one shot thing, tho i think i may have remembered it being. still not sure, tho. i may have just ran out of one or the other. it's kind of ironic if it is tolerance-developing, as memantine or NMDA antagonism in general, is supposed to be anti-tolerance-developing, right?
ugh. just checking, i always write "developing" as "developping." odd that i do that, i'm not even francophone by any stretch, i just went to french immersion in high school and before.
poster:iforgotmypassword
thread:800592
URL: http://www.dr-bob.org/babble/20071213/msgs/800718.html