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Re: Apathy from SSRIs -- any suggestions?

Posted by cactus on August 2, 2007, at 22:36:49

In reply to Apathy from SSRIs -- any suggestions?, posted by Racer on August 1, 2007, at 15:43:56

> I'm taking Wellbutrin, Concerta, Prozac, and SAMe, which is working well enough, I guess, but I'm experiencing a good deal of SSRI-related apathy and sleep disturbance. The apathy is a problem, because it's not neutral apathy -- I'm definitely in a kind of "I'm depressed, but I don't care" sort of a state. Although, I don't know if it's really depression, rather than just a "oh, f--k it all, I just don't give a rat's behind" sort of a state.
>
> As many of you might know, I've taken many, many different antidepressants. My dx is major depession, unipolar; anorexia nervosa; and generalized anxiety disorder. I also have {ahem} "obsessive compulsive personality traits," and am on the cusp of diagnosable OCD -- actually, it's only lately that I brought that up with my T, and haven't actually discussed it with my pdoc, so maybe it's not a "cusp" thing at all.
>
> I'm debating dropping the Prozac entirely, although I know that the WB/stim combo isn't quite enough to fix me.
>
> So, can anyone offer any other suggestions? Might Zoloft be a better choice for SSRI? (The other SSRIs are out -- been there, done that, they're worse. Effexor and Cymbalta, ditto.) My pdoc says that he thinks I do need a serotinergic component, and I think he's probably right. But I'm just not satisfied by where I am now. I've got that feeling as though I really want to sit here and cry, but it seems to much trouble even to finish a thought, let alone bother with having an emotion.
>
> Thanks.

Hey there racer, hope you're ok. I recently started zoloft and it's had the least side effects of any ssri I have ever taken. It's been about 6 weeks now and the ssri apathy has returned BUT it is nowhere near as bad as any of the others I have tried, which like you has been quite a few. I only have lexapro and cymbalta left on the list. It's reportedly weight neutral and I have lost weight since starting it. Anyway it's been the best for me so far. I would recommend it hon!!

 

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