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Re: Trileptol and Seroquel questions

Posted by Sandra62 on March 25, 2007, at 16:05:31

In reply to Re: Trileptol and Seroquel questions » Reggie BoStar, posted by Phillipa on March 24, 2007, at 23:07:58

Reggie I only have experience with Seroquel taken at bedtime only. I started with 25 mg and it knocked me flat. I could sleep for hours. My PDOC said that raising the dosage often helps to eliminate the sleep elixir effect so we eventually titrated up to 300 mg. I still was unconcious within the hour, went to bed before midnight and slept until noon, and then along with it came daytime anxiety. My PDOC was puzzled by this as it is supposed to have the opposite effect so she called the pharmaceutical company and they indeed had reports of a paradoxical reaction with anxiety, albiet this was at 600 mg or more. I am extremely med sensitive so it made sense that I was experiencing this at 'only' 300 mg. I had to stop Seroquel. It did nothing for my Bipolar. 10 mg of Zyprexa at bedtime works like a charm for me but I am experiencing 'blunting' and of course have had the dreaded weight gain. So it's on to Topamax for me. Good luck!


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