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Re: Do you have to get a lot worse before better?

Posted by notfred on February 2, 2007, at 8:46:51

In reply to Re: Do you have to get a lot worse before better? » Quintal, posted by blueberry1 on February 2, 2007, at 4:49:02

> Thanks for the input. I appreciate it. I have always believed that the closer a drug is to targeting the real problem, the quicker it will work and with less side effects. The farther it is away from the real problem, the longer it takes and more side effects, due to downstream adjustments rather than hitting a bullseye. There are clinical studies that show that. Two of them at pubmed. I just dond't have what it takes right now to go find them.
>


For me this is not true. All AD's take ~6 weeks to begin to work. I have been mostly in remission for 2 decades so the AD's do work quite well once they start working. All AD suck, with side effects, for the first few week, for me.

I would not hold up studies as being the end all and be all, given we still do not know why AD's work. Nothing is proven, all is theory. The same goes for a biochemical model for depression or any MI for that matter.


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