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Beware Abilify augmentation

Posted by psychobot5000 on October 3, 2006, at 14:45:54

This is my account of a nasty experience trying abilify for treatment-resistant depression.

On paper it looks good, as atypical antipsychotics are known to help with depression, and abilify/aripiprazole has a better looking profile than most (D2 partial agonism, rather than antagonism, 5ht2 blocking, 5ht1a agonism). It is also considered a 'nonsedating' antipsychotic.

Well, my experience was frankly awful (on 5-10mg/day). At first I thought I was sick. Side-effects included: somnolence, increased time in bed, physical weakness, nausea, and reduced awareness. It was awful, and I struggled to get by. Add to this that abilify has a damnably long half-life of 75 hours--once you take it, you're stuck with the stuff for several days.

I went off it for about six days, then tried one more dose, and all the nastiness came back. I do not recommend this medication.

P-bot


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poster:psychobot5000 thread:691519
URL: http://www.dr-bob.org/babble/20061003/msgs/691519.html