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Re: INDERAL LA discontinued? » SandyWeb

Posted by yxibow on September 8, 2006, at 6:45:39

In reply to Re: INDERAL LA discontinued?, posted by SandyWeb on September 7, 2006, at 22:31:33

> I found this on the Health Canada's website for discontinued medications:
>
> http://search.hc-sc.gc.ca/cgi-bin/query?mss=hc%2Fdpd%2Fenglish%2Fdiscontinued%2Fsimple&pg=q&what=web&kl=XX&enc=iso88591&site=main&filter=product&q=inderal+la&search=Search
>
> I hope that link works.
>
> It shows all the doses, with a date of September 1, 2006.
>
> Maybe they are still available in the US, but for some reason I guess we aren't allowed them in Canada anymore.
>
> Sandy


Generics:

PMS-PROPRANOLOL 80MG
http://www.hc-sc.gc.ca/hpb/drugs-dpd/product/p5309.html

NU-PROPRANOLOL 80MG
http://www.hc-sc.gc.ca/hpb/drugs-dpd/product/p14934.html

DOM-PROPRANOLOL 80MG
http://www.hc-sc.gc.ca/hpb/drugs-dpd/product/p20305.html


The generics remain covered from what I can see in Health Canada's database in different strengths, the long acting is no longer covered. In the US, It appears that Wyerst themselves has discontinued the long acting formula.

ESI Lederle makes the drug though, which is a subsidiary of Wyerst.

It appears there is now "InnoPranXL", a generic
substitute in the US made by Reliant
(http://www.innopranxl.com/) if you check Eckerd.

If you link to http://www.hc-sc.gc.ca/drug2/product/p16124.html
Inderal LA 120 MG, it makes no mention of discontinuation.

I would ask your pharmacist. I would agree that going from a long acting to multiple doses would be annoying but propranolol has been generic for years in both countries -- it was simply patent renewed as an extended release format. Sales may not have been as expected. It is produced as much as generic benzodiazepines and was first introduced to the market in 1967.

It was first approved as an extended release in 1983. The last labelling revision which I cannot figure out exactly what they're talking about was in July of 2004.

You can search any drug approved by the FDA since the dawn of time, with extended information starting in 1984, at Drugs@FDA
http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

Depending on records, you may or may not be able to see drugs back to the 1950s. E.g. Thorazine, November 1957. Valium, November 11, 1963. Etc.

 

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