Posted by Glydin on July 20, 2006, at 16:33:59
In reply to Re: New AD warnings in US?, posted by caraher on July 20, 2006, at 16:14:22
> I'm curious what the risk would be otherwise - is this a tenfold, 50% or 5% increase in risk of this particular complication?
>~~~ From what I can tell, the conclusions are saying it's is on the order of 5-6 times higher for risk of PPHN. I have being quite discerning in looking at these stats as in 25 years of experience, I've seen initial studies not bear fruit when held to closer observation. And this one was a retrospective data gathering. I would like more data and some investigations as to what is the etiology.
> I have no ax to grind here, and neither of these warnings affects me directly.
~~~ Didn't think ya did. (smile)
> But there are obviously lots of women on these drugs who will become pregnant and who will have to make decisions about risks.
~~~ Finding what we doing in terms of fetal impact has to be done. I'm just not sure about this particular one.... yet. We do know some of the outcomes for untreated depressive disorders in Mothers.
>
> Also... did the study conclude that there was no significant effect due to SSRI use before 20 weeks? That would be good to know!~~~ Yep, and it's also quite interesting as most tetragenic effects happen early in development. Of course, tetragenesis and structural physiological changes probably would not equate in this case.
poster:Glydin
thread:668509
URL: http://www.dr-bob.org/babble/20060717/msgs/668672.html