Posted by ed_uk on May 29, 2006, at 4:10:17
In reply to Re: Low Dose Prozac with OCD » Larry Hoover, posted by saturn on May 28, 2006, at 21:55:53
Hi Saturn,
One of the initial clinical trials for fluoxetine examined the effectiveness of 5mg, 20mg and 40mg in the treatment of depressive illness. 354 patients were included in this trial. Effectiveness was assessed using the HAM-D rating scale. The trial lasted 6 weeks. In this trial, 5mg, 20mg and 40mg were all more effective than placebo. There was no evidence that the higher doses were more effective than 5mg.
The efficacy of 20mg fluoxetine has been studied in a greater number of patients than 5mg, which is why the manufacturer decided that 20mg would be the 'standard dose'.
Ed
poster:ed_uk
thread:642053
URL: http://www.dr-bob.org/babble/20060525/msgs/650010.html