Posted by SLS on May 27, 2006, at 9:43:27
In reply to Cymbalta halflife and dosage timing, posted by llrrrpp on May 27, 2006, at 0:48:17
Hi there.
I'm disappointed to hear that you are experiencing what seems like withdrawal symptoms. I never liked the idea of dosing Cymbalta only once a day. Like Effexor and Paxil, Cymbalta has a relatively short half-life. Many people find that it is critical not to miss a dose with these drugs. You might profit from splitting the dosage into 30mg in the morning and 30mg in the evening. Either that or add another 30mg in the morning for a total of 90mg per day. In the meantime, try to take your dose of Cymbalta at the same time each day.
- Scott> So I've been taking 30 mg of cymbalta for the first 7 days, followed by 60 mg of cymbalta for the next 16 days. I take cymbalta at night for MDD. I also take 25-50 mg seroquel in the evening for sleep. These are the only meds I have ever taken, so I am still trying to figure out what they're all about (haha, me and the pdocs!)
>
> Well here's my question: If I stay up a little late (like right now it's almost 2 am EST!) and I haven't taken cymbalta in 24 hours, I feel kind of like a druggy feeling. Kind of like when I turn my head, it takes my perception just a split second to catch up. Also, I noticed that my balance or equilibrium feels a little funny in the late evening, and that my mood worsens (this could be a function of lifestyle, however, because the evenings are a lonely time.)
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> Is it possible that I don't have enough cymbalta in my system late in the day? Can I expect these effects (very mild and not noxious) to go away? Anyone else experience something like this?
poster:SLS
thread:649206
URL: http://www.dr-bob.org/babble/20060525/msgs/649294.html