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Re: Could initial response come back?

Posted by SLS on May 25, 2006, at 7:33:48

In reply to Could initial response come back?, posted by addinbc on May 25, 2006, at 2:54:39

> I am really in need of some moral support here please :)
>
> I am giving Reboxetine another try. My initial response to the drug after a couple of days on it was great! I had energy, and felt really really good! That disappeared the next day, and I seemed to be getting more depressed on it.


I wouldn't presume to be able to predict with certainty how you will respond to reboxetine.

My experience with it was negative. It made my depression worse and produced suicidal ideation within the first two weeks. I decided that the degree of worsening was far too much to justify continuing with the drug.

Sometimes, an initial brief improvement seen within the first week is an indicator of an eventual positive response. Reboxetine might yet prove effective for you.

Right now, my opinion of reboxetine is unfavorable. My first reaction to your described experience is that reboxetine will continue to make your depression worse and perhaps even introduce anxiety that was previously absent. I hope I'm wrong. The only way to know for sure is to titrate gradually up to 6-8mg and remain at that dosage for several weeks. If you respond quickly to a lower dosage, that's great. Hopefully, the improvements you see with ADD symptoms will continue.

Today, I encourage you to continue with reboxetine. Other people have had success with it. You will have to evaluate on a day by day basis whether or not the drug is producing a significant worsening of your condition. If it is not, then you will need to be as patient with this drug as you would be with any other antidepressant. Even in an ideal scenario, one would not expect to see a true antidepressant response for 2-3 weeks. It is likely that it will take longer than that.


- Scott


 

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poster:SLS thread:648249
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