Posted by Crazy Horse on April 21, 2006, at 8:52:53
In reply to Re: ENSAM Patch, parnate or nardil? » Phillipa, posted by Caedmon on April 21, 2006, at 8:40:15
> Hi Phillipa, here is what I understand about the three, others are welcome to add their input:
>
> EMSAM:
> + Easy, once daily application
> + Energizing, helpful for memory(?)
> + No diet restrictions
> + Motivating antidepressant
> - Little research on anxiolytic properties
> - Expensive
> - New, so some adverse reactions may be underreported
> - May cause agitation and insomnia
> 0 Usually causes slight weight loss
> 0 Still has the usual drug restrictions
> 0 Some amphetamine-like qualities
> 0 Brand-name ("Emsam") sounds much less dorky compared to the other MAOIs :p
>
> PARNATE:
> + Very motivating, effective antidepressant
> + Some research as being good for social phobia, panic disorder
> + Easiest to augment?
> + Small doses = easier titration
> + Usually very fast-acting
> - May cause agitation and insomnia
> - Often requires multiple daily dosing
> - Less forgiving of diet restrictions vs. Nardil
> 0 Usually weight neutral or causes weight loss
> 0 Some amphetamine-like qualities
> 0 Sedates some, activates others
>
> NARDIL:
> + LOTS of research shows it helps anxiety
> + More forgiving of diet restrictions vs. Parnate
> + Bonus: good drug for those with high blood pressure
> + Metabolite increases GABA in parts of brain
> - May cause major side effects: sexual, weight gain, hypotension
> - Least forgiving of drug interactions (?)
> - Takes a little longer to kick in vs. other MAOIs
> 0 Most people either love it or hate it
> 0 Usually not very activating
>
> ______________
> Maybe that helps in making the decision? I tried to be impartial in my assessment. For me, Parnate had the profile that best matched what I needed so I'm trying that out. Best of luck,
>
> - CGreat job C! Well, hopefully Parnate will work a long time for me, but if not EMSAM is definitely my next med...dang look at that profile!
Monte
poster:Crazy Horse
thread:635047
URL: http://www.dr-bob.org/babble/20060417/msgs/635483.html